发明申请
- 专利标题： SMALL MOLECULE INHIBITORS OF MDM2 AND THE USES THEREOF
- 专利标题（中）： MDM2的小分子抑制剂及其用途
-
申请号： US12822829申请日： 2010-06-24
-
公开(公告)号： US20100273799A1公开(公告)日： 2010-10-28
- 发明人: Shaomeng Wang , Ke Ding , Yipin Lu , Zaneta Nikolovska-Coleska , Su Qiu , Guoping Wang , Dongguang Qin , Sanjeev Kumar
- 申请人： Shaomeng Wang , Ke Ding , Yipin Lu , Zaneta Nikolovska-Coleska , Su Qiu , Guoping Wang , Dongguang Qin , Sanjeev Kumar
- 申请人地址： US MI Ann Arbor
- 专利权人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 当前专利权人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 当前专利权人地址： US MI Ann Arbor
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/407 ; A61P35/00 ; C07D487/10 ; C07D401/14 ; A61K31/496 ; C07D413/14 ; C12N5/02
摘要：
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
公开/授权文献
- US08088931B2 Small molecule inhibitors of MDM2 and the uses thereof 公开/授权日：2012-01-03
信息查询
IPC分类:
