发明申请
- 专利标题： DIAZO BICYCLIC SMAC MIMETICS AND THE USES THEREOF
- 专利标题（中）： DIAZO BICYCLIC SMAC MIME及其用途
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申请号： US12159249申请日： 2008-04-14
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公开(公告)号： US20100273812A1公开(公告)日： 2010-10-28
- 发明人: Shaomeng Wang , Yuefeng Peng , Haiying Sun , Qian Cai , Zaneta Nikolovska-Coleska , Jianfeng Lu , Su Qiu
- 申请人： Shaomeng Wang , Yuefeng Peng , Haiying Sun , Qian Cai , Zaneta Nikolovska-Coleska , Jianfeng Lu , Su Qiu
- 申请人地址： US MI Ann Arbor
- 专利权人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 当前专利权人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 当前专利权人地址： US MI Ann Arbor
- 国际申请： PCT/US08/60215 WO 20080414
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; C07D487/04 ; A61K31/407 ; A61K31/4025 ; A61K31/4439 ; A61P35/00 ; C12N5/00
摘要：
The invention relates to diazo bicyclic mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
公开/授权文献
- US08278293B2 Diazo bicyclic Smac mimetics and the uses thereof 公开/授权日：2012-10-02
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