发明申请
- 专利标题： GENES ASSOCIATED WITH CHEMOTHERAPY RESPONSE AND USES THEREOF
- 专利标题（中）： 与化疗反应有关的基因及其用途
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申请号： US12307114申请日： 2007-06-28
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公开(公告)号： US20100284915A1公开(公告)日： 2010-11-11
- 发明人: Hongyue Dai , Chunsheng Zhang , Andrey Loboda
- 申请人： Hongyue Dai , Chunsheng Zhang , Andrey Loboda
- 国际申请： PCT/US07/15025 WO 20070628
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; C12Q1/68 ; C40B30/00 ; A61K31/713 ; A61K31/7105 ; A61K38/02 ; A61K39/395 ; A61K31/513 ; A61K31/675 ; A61K31/337 ; A61K31/7048 ; A61K31/282 ; C12N5/07 ; C12N5/071 ; C40B40/08 ; A61K31/7088 ; A61P35/00
摘要：
The invention provides molecular markers that are associated with responsiveness of a cancer patient to a chemotherapy treatment, and methods and computer systems for determining such responsiveness based on measurements of these molecular markers. The present invention also provides methods and compositions for enhancing the efficacy of chemotherapies in patients by modulating the expression or activity of genes encoding these molecular markers and/or their encoded proteins.
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