发明申请
- 专利标题: MEASUREMENT OF VITAMIN D
- 专利标题(中): 维生素D的测定
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申请号: US12326972申请日: 2008-12-03
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公开(公告)号: US20100285603A1公开(公告)日: 2010-11-11
- 发明人: Uwe Kobold , Thomas Duelffer , Michael Grol , Rupert Herrmann , Herbert Von der Eltz , Leopold Von Proff
- 申请人: Uwe Kobold , Thomas Duelffer , Michael Grol , Rupert Herrmann , Herbert Von der Eltz , Leopold Von Proff
- 优先权: EP06011605.0 20060606
- 主分类号: G01N33/00
- IPC分类号: G01N33/00
摘要:
The present invention relates to a method of measuring a vitamin D metabolite in a sample, the method comprising the steps of (a) treating said sample with a vitamin D metabolite releasing reagent under conditions appropriate to release a vitamin D metabolite from vitamin D-binding protein and not to cause protein precipitation, (b) subjecting the treated sample obtained in step (a) to a chromatographic separation, and (c) measuring a vitamin D metabolite during or after said chromatographic separation. The present invention also relates to methods for determining the vitamin D status of a subject, for use in the diagnosis of disease, and to agents and kits for use in performing the methods of the invention.
公开/授权文献
- US08003400B2 Measurement of vitamin D 公开/授权日:2011-08-23