- 专利标题: GABA NEURON PROGENITOR CELL MARKER 65B13
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申请号: US12524153申请日: 2008-02-07
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公开(公告)号: US20100303771A1公开(公告)日: 2010-12-02
- 发明人: Yuichi Ono , Yasuko Nakagawa , Eri Mizuhara
- 申请人: Yuichi Ono , Yasuko Nakagawa , Eri Mizuhara
- 申请人地址: JP Bunkyo-ku
- 专利权人: Eisai R & D Management Co., Ltd.
- 当前专利权人: Eisai R & D Management Co., Ltd.
- 当前专利权人地址: JP Bunkyo-ku
- 优先权: JP2007-031075 20070209
- 国际申请: PCT/JP2008/052039 WO 20080207
- 主分类号: A61K35/30
- IPC分类号: A61K35/30 ; C12Q1/68 ; G01N33/68 ; G01N33/567 ; C12N5/0797 ; C07H21/00 ; C07K16/18 ; C07H21/04 ; A61P25/00 ; A61P25/28
摘要:
The present inventors identified a selective marker 65B13 for GABA neuron progenitor cells of the spinal dorsal horn and cerebellum, and successfully isolated GABA neuron progenitor cells using antibodies that bind to a protein encoded by the gene. 65B13 was demonstrated to be useful as a marker to isolate GABA-producing neuron progenitor cells in the spinal dorsal horn and cerebellum. GABA neuron progenitor cells can be efficiently identified or isolated by using the identified marker as an indicator.
公开/授权文献
- US08609405B2 GABA neuron progenitor cell marker 65B13 公开/授权日:2013-12-17
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