发明申请
- 专利标题： Recombinant Cell Clones Having Increased Stability and Methods of Making and Using the Same
- 专利标题（中）： 增加稳定性的重组细胞克隆及其制备和使用方法
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申请号： US12848897申请日： 2010-08-02
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公开(公告)号： US20100317055A1公开(公告)日： 2010-12-16
- 发明人: Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人： Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人地址： AT Vienna
- 专利权人： Baxter Aktiengesellschaft
- 当前专利权人： Baxter Aktiengesellschaft
- 当前专利权人地址： AT Vienna
- 优先权： ATA1073/97 19970620
- 主分类号： C12P21/02
- IPC分类号： C12P21/02
摘要：
Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
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