- 专利标题： METHODS OF TREATING CANCER USING IL-21
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申请号： US12771667申请日： 2010-04-30
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公开(公告)号： US20100322898A1公开(公告)日： 2010-12-23
- 发明人: Andrew J. Nelson , Steven D. Hughes , Richard D. Holly
- 申请人： Andrew J. Nelson , Steven D. Hughes , Richard D. Holly
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 主分类号： A61K38/20
- IPC分类号： A61K38/20 ; A61K38/21 ; A61K35/12 ; A61P35/00
摘要：
Methods for treating mammals with cancer using molecules that have an IL-21 functional activity are described. The molecules having IL-21 functional activities include polypeptides that have homology to the human IL-21 polypeptide sequence and proteins fused to a polypeptide with IL-21 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer therapeutics.