发明申请
- 专利标题: MODULATION OF SGLT2 EXPRESSION
- 专利标题(中): SGLT2表达的调控
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申请号: US12145470申请日: 2008-06-24
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公开(公告)号: US20100324122A1公开(公告)日: 2010-12-23
- 发明人: Susan M. Freier , Edward Wancewicz , Brett P. Monia , Andrew M. Siwkowski , Lynnetta Watts , Thomas A. Leedom
- 申请人: Susan M. Freier , Edward Wancewicz , Brett P. Monia , Andrew M. Siwkowski , Lynnetta Watts , Thomas A. Leedom
- 申请人地址: US CA Carlsbad
- 专利权人: ISIS PHARMACEUTICALS, INC.
- 当前专利权人: ISIS PHARMACEUTICALS, INC.
- 当前专利权人地址: US CA Carlsbad
- 主分类号: A61K31/713
- IPC分类号: A61K31/713 ; C07H21/04 ; A61P3/10 ; A61P35/00 ; C12N5/071 ; C12Q1/68
摘要:
Compounds, compositions and methods are provided for modulating the expression of SGLT2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding SGLT2. Methods of using these compounds for modulation of SGLT2 expression and for diagnosis and treatment of diseases and conditions associated with expression of SGLT2 are provided.
公开/授权文献
- US08084436B2 Modulation of SGLT2 expression 公开/授权日:2011-12-27
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