- 专利标题: Mitotic kinesin inhibitors and methods of use thereof
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申请号: US12822066申请日: 2010-06-23
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公开(公告)号: US20100331283A1公开(公告)日: 2010-12-30
- 发明人: Jeremy Hans , Eli M. Wallace , Qian Zhao , Shelley Allen , Ellen Laird , Joseph P. Lyssikatos , John E. Robisnson , Christopher P. Corrette , Robert Kirk DeLisle , Walter C. Voegtti
- 申请人: Jeremy Hans , Eli M. Wallace , Qian Zhao , Shelley Allen , Ellen Laird , Joseph P. Lyssikatos , John E. Robisnson , Christopher P. Corrette , Robert Kirk DeLisle , Walter C. Voegtti
- 申请人地址: US CO Boulder
- 专利权人: Array BioPharma Inc.
- 当前专利权人: Array BioPharma Inc.
- 当前专利权人地址: US CO Boulder
- 主分类号: A61K31/675
- IPC分类号: A61K31/675 ; C07D417/04 ; C07D513/04 ; C07D419/04 ; C07D471/04 ; C07D487/04 ; C07D495/04 ; C07F9/06 ; C07D417/14 ; A61K31/433 ; A61K31/437 ; A61K31/4439 ; A61K31/506 ; A61K31/5377 ; A61K31/541 ; A61K31/5355 ; A61K31/542 ; A61K31/4985 ; A61K31/5025 ; A61K31/519 ; A61K31/454 ; A61P35/00 ; A61P31/10 ; A61P37/00 ; A61P29/00 ; A61P9/00
摘要:
This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.
公开/授权文献
- US08268871B2 Mitotic kinesin inhibitors and methods of use thereof 公开/授权日:2012-09-18
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