发明申请
- 专利标题: TRIAZONE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
- 专利标题(中): 调节HSP90活性的TRIAZONE化合物
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申请号: US12604970申请日: 2009-10-23
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公开(公告)号: US20110009397A1公开(公告)日: 2011-01-13
- 发明人: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh U. Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard P. Ng , Kevin Foley , Zhenjian Du , James Barsoum
- 申请人: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh U. Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard P. Ng , Kevin Foley , Zhenjian Du , James Barsoum
- 专利权人: Synta Pharmaceuticals Corp.
- 当前专利权人: Synta Pharmaceuticals Corp.
- 主分类号: A61K31/4196
- IPC分类号: A61K31/4196 ; A61K31/4709 ; A61K31/4439 ; A61K31/4725 ; A61K31/5377 ; A61K31/538 ; C12N5/00
摘要:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- US09090569B2 Triazone compounds that modulate HSP90 activity 公开/授权日:2015-07-28
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