发明申请
US20110027297A1 Methods Involving MS4A12 and Agents Targeting MS4A12 for Therapy, Diagnosis and Testing
审中-公开
涉及MS4A12和靶向MS4A12的药物用于治疗，诊断和测试的方法
- 专利标题： Methods Involving MS4A12 and Agents Targeting MS4A12 for Therapy, Diagnosis and Testing
- 专利标题（中）： 涉及MS4A12和靶向MS4A12的药物用于治疗，诊断和测试的方法
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申请号： US12937178申请日： 2009-03-30
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公开(公告)号： US20110027297A1公开(公告)日： 2011-02-03
- 发明人: Ugur Sahin , Ozlem Tureci , Michael Koslowski
- 申请人： Ugur Sahin , Ozlem Tureci , Michael Koslowski
- 优先权： EP08007109.5 20080410
- 国际申请： PCT/EP2009/002309 WO 20090330
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07H21/02 ; C07H21/00 ; C07K16/28 ; A61K31/713 ; A61K31/7088 ; C12N5/071 ; C12Q1/68 ; C12Q1/02 ; G01N33/566 ; A61P35/00 ; A61P35/04
摘要：
The invention relates to methods involving MS4A12 and agents targeting MS4A12 which are useful for therapy, diagnosis and testing of disease states, in particular cancer diseases. In particular, the invention relates to agents which reduce or inhibit expression or activity of MS4A12, compositions containing these agents, and methods for reducing, determining, or increasing the responsiveness of a cell towards EGF.