发明申请
- 专利标题： GENE ENCODING CHONDROITINASE ABC AND USES THEREFOR
- 专利标题（中）： 基因编码基因ABC及其用途
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申请号： US12712960申请日： 2010-02-25
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公开(公告)号： US20110027860A1公开(公告)日： 2011-02-03
- 发明人: Nobuyuki SATO , Masahiko SHIMADA , Hiroshi ODA
- 申请人： Nobuyuki SATO , Masahiko SHIMADA , Hiroshi ODA
- 申请人地址： JP Tokyo
- 专利权人： MARUHA NICHIRO SEAFOODS, INC.
- 当前专利权人： MARUHA NICHIRO SEAFOODS, INC.
- 当前专利权人地址： JP Tokyo
- 优先权： JP5-35810 19930224
- 主分类号： C12N9/88
- IPC分类号： C12N9/88 ; C07H21/00 ; C12N15/63 ; C12N5/10
摘要：
Nucleic acid sequences coding for the chondroitinase ABC gene and isolated chondroitinase ABC protein produced in a host cell transformed with a nucleic acid vector directing the expression of a nucleotide sequence coding for chondroitinase ABC protein are described. Chondroitinase ABC prepared by chemical synthesis is also described. Monoclonal and polyclonal antibodies which are specifically reactive with chondroitinase ABC protein are disclosed. The isolated chondroitinase ABC can be used in methods of treating intervertebral disc displacement, promoting neurite regeneration, and detecting galactosaminoglycans.
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