发明申请
- 专利标题: COATING COMPOSITION FOR THE DIP COATING OF CAPSULE HALVES
- 专利标题(中): 涂料组合物用于胶囊的浸涂
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申请号: US12845994申请日: 2010-07-29
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公开(公告)号: US20110033530A1公开(公告)日: 2011-02-10
- 发明人: Brigitte SKALSKY , Manfred Assmus , Odette Hensel , Hans-Ulrich Petereit
- 申请人: Brigitte SKALSKY , Manfred Assmus , Odette Hensel , Hans-Ulrich Petereit
- 申请人地址: DE Darmstadt
- 专利权人: Evonik Roehm GmbH
- 当前专利权人: Evonik Roehm GmbH
- 当前专利权人地址: DE Darmstadt
- 主分类号: A61K9/48
- IPC分类号: A61K9/48 ; A61K47/32 ; B05D5/00 ; A23P1/08
摘要:
A coating composition for the enteric coating of capsule halves made of water-soluble or water-swellable polymer material in a dipping process is provided. The composition is an aqueous dispersion or solution, containing a polymer mixture of at least one first (meth)acrylate copolymer, which is enteric, and at least one further (meth)acrylate copolymer, which is enteric or water-insoluble, and also auxiliaries which influence the viscosity of the dispersion and the elasticity of the dried polymer film. The solids content of the dispersion or solution is more than 25% by weight and the viscosity is 150 to 1500 mPa·s and a dried film produced from the dispersion or solution has an elongation at break of at least 200%. Also provided is a capsule composed of two capsule halves coated with the dispersion or solution in a dipping process does. The enteric capsule does not dissolve in 0.1 N HCl at pH 1.2 after two hours, but completely dissolves in buffer at pH 6.8 in less than 30 minutes. A method to prepare enteric coated capsule halves is also provided.
公开/授权文献
- US09107451B2 Coating composition for the dip coating of capsule halves 公开/授权日:2015-08-18
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