发明申请
US20110053940A1 3,4-SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS
有权
作为RININ抑制剂的3,4-取代的哌啶衍生物
- 专利标题： 3,4-SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS
- 专利标题（中）： 作为RININ抑制剂的3,4-取代的哌啶衍生物
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申请号： US12990927申请日： 2009-05-04
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公开(公告)号： US20110053940A1公开(公告)日： 2011-03-03
- 发明人: Austin Chih-Yu Chen , Daniel Dube , Pierre-Andre Fournier , Erich L. Grimm , Patrick Lacombe , Sebastien Laliberte , Dwight MacDonald , D. Bruce MacKay , Daniel James McKay , Tom Yao-Hsiang Wu , Louis-Charles Campeau , Jeremy Peter Scott , Nadine Bremeyer
- 申请人： Austin Chih-Yu Chen , Daniel Dube , Pierre-Andre Fournier , Erich L. Grimm , Patrick Lacombe , Sebastien Laliberte , Dwight MacDonald , D. Bruce MacKay , Daniel James McKay , Tom Yao-Hsiang Wu , Louis-Charles Campeau , Jeremy Peter Scott , Nadine Bremeyer
- 国际申请： PCT/CA09/00611 WO 20090504
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; C07D401/04 ; C07D401/14 ; C07D413/14 ; A61K31/5377 ; A61K31/4709 ; A61K31/4725 ; A61P9/12 ; A61P9/00 ; A61P27/02 ; A61P25/00 ; A61P11/00 ; A61P9/10 ; A61P13/12
摘要：
The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.
公开/授权文献
- US08889714B2 3,4-substituted piperidine derivatives as renin inhibitors 公开/授权日：2014-11-18