发明申请
- 专利标题： COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS
- 专利标题（中）： 用于治疗增生性疾病的化合物
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申请号： US12883883申请日： 2010-09-16
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公开(公告)号： US20110059893A1公开(公告)日： 2011-03-10
- 发明人: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人： Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 主分类号： A61K38/06
- IPC分类号： A61K38/06 ; A61K31/675 ; A61K31/501 ; A61K31/4725 ; A61K31/4709 ; A61K31/4439 ; A61K31/42 ; C07K5/08 ; C07F9/09 ; C07D261/08 ; C07D413/10 ; C07D413/04 ; A61K31/422 ; A61P35/00 ; A61P7/00 ; A61P27/02
摘要：
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US08269017B2 Compounds for the treatment of proliferative disorders 公开/授权日：2012-09-18
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