发明申请
US20110065205A1 METHOD FOR DETERMINING PROGNOSIS OF ACUTE CENTRAL NERVOUS SYSTEM DISORDER
审中-公开
确定急性中枢神经系统疾病预后的方法
- 专利标题: METHOD FOR DETERMINING PROGNOSIS OF ACUTE CENTRAL NERVOUS SYSTEM DISORDER
- 专利标题(中): 确定急性中枢神经系统疾病预后的方法
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申请号: US12532245申请日: 2008-03-27
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公开(公告)号: US20110065205A1公开(公告)日: 2011-03-17
- 发明人: Tsuyoshi Maekawa , Tomonori Izumi , Yasutaka Oda , Yuki Akiyoshi
- 申请人: Tsuyoshi Maekawa , Tomonori Izumi , Yasutaka Oda , Yuki Akiyoshi
- 申请人地址: JP Yamaguchi JP Tokyo
- 专利权人: YAMAGUCHI UNIVERSITY,NANO SOLUTION, INC.,
- 当前专利权人: YAMAGUCHI UNIVERSITY,NANO SOLUTION, INC.,
- 当前专利权人地址: JP Yamaguchi JP Tokyo
- 优先权: JP2007-091600 20070330
- 国际申请: PCT/JP2008/055930 WO 20080327
- 主分类号: G01N33/566
- IPC分类号: G01N33/566 ; C07K16/18 ; C07K16/06
摘要:
The present invention has its main object of providing a method for determining prognosis scientifically by searching an early marker for predicting neurological prognosis in order to grasp the disease state of a patient with an acute central nervous system disorder in the early stage and enabling an appropriate treatment to be performed. The method for determining the prognosis is provided in which the expression level of SH3BGRL3 in the biological fluid of the patient within 48 hours after resuscitation from cardiopulmonary arrest is measured, and the prognosis of the disorder classified into a good prognosis group and a poor prognosis group depending on the expression level or the presence or absence of the expression based on the Glasgow Outcome Scale (GOS) is predicted.
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