A differential serial communication transmitter (i.e. PCI Express or other suitable type of transmitter) can be used to transport and interoperate transition minimized differential signaling. The differential serial communication transmitter control logic receives display configuration control data and in response configures at least one differential serial communication transmitter of a plurality of differential serial communication transmitters in an integrated circuit for communication with a display (i.e. visual digital display) employing transition minimized differential signaling. For example, the integrated circuit, such as a graphics processor, may include the plurality of differential serial communication transmitters for communication with devices, such as a northbridge circuit and a display within a computer system. The differential serial communication transmitter control logic may configure at least one of the plurality of differential serial communication transmitters for communication with the display via a differential serial communication display link (i.e. DVI or other suitable type of link). The plurality of differential serial communication transmitters may also be configured for communication with one or more other devices, such as with a bridge circuit such as a northbridge.