发明申请
US20110082144A1 N-HETEROARYL INDOLE CARBOXAMIDES AND ANALOGUES THEREOF, FOR USE AS GLUCOKINASE ACTIVATORS IN THE TREATMENT OF DIABETES
有权
N-羟基吲哚类化合物及其类似物，用作治疗糖尿病的糖尿病激活剂
- 专利标题： N-HETEROARYL INDOLE CARBOXAMIDES AND ANALOGUES THEREOF, FOR USE AS GLUCOKINASE ACTIVATORS IN THE TREATMENT OF DIABETES
- 专利标题（中）： N-羟基吲哚类化合物及其类似物，用作治疗糖尿病的糖尿病激活剂
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申请号： US12895761申请日： 2010-09-30
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公开(公告)号： US20110082144A1公开(公告)日： 2011-04-07
- 发明人: Jesper F. Lau , Per Vedsø , János Tibor Kodra , Anthony Murray , Lone Jeppesen , Michael Ankersen , Govindan Subramanian , Adnan M. M. Mjalli , Robert Carl Andrews , Dharma Rao Polisetti , Daniel Peter Christen
- 申请人： Jesper F. Lau , Per Vedsø , János Tibor Kodra , Anthony Murray , Lone Jeppesen , Michael Ankersen , Govindan Subramanian , Adnan M. M. Mjalli , Robert Carl Andrews , Dharma Rao Polisetti , Daniel Peter Christen
- 申请人地址： US NC High Point
- 专利权人： TransTech Pharma, Inc.
- 当前专利权人： TransTech Pharma, Inc.
- 当前专利权人地址： US NC High Point
- 优先权： EP03388079.0 20031124
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D403/12 ; A61K31/427 ; C07D471/04 ; A61K31/437 ; C07D403/14 ; A61K31/506 ; C07D401/14 ; A61K31/4439 ; C07D413/14 ; A61P3/10
摘要：
This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. The compounds are of the general formula (I) wherein A and B are further defined in the application.