发明申请
US20110105998A1 SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS
有权
用于目标细胞光刺激的系统,方法和组合物
- 专利标题: SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS
- 专利标题(中): 用于目标细胞光刺激的系统,方法和组合物
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申请号: US12988567申请日: 2009-04-08
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公开(公告)号: US20110105998A1公开(公告)日: 2011-05-05
- 发明人: Feng Zhang , Karl Deisseroth , Viviana Gradinaru
- 申请人: Feng Zhang , Karl Deisseroth , Viviana Gradinaru
- 申请人地址: US CA Palo Alto
- 专利权人: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO
- 当前专利权人: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO
- 当前专利权人地址: US CA Palo Alto
- 国际申请: PCT/US2009/039949 WO 20090408
- 主分类号: A61N5/06
- IPC分类号: A61N5/06 ; A61M37/00 ; C12N5/02 ; C12Q1/02 ; C12N13/00 ; C12N15/63 ; C07H21/04 ; C12N5/00 ; A61P25/16
摘要:
Methods, systems and devices are implemented in connection with light-responsive ion channel molecules. One such method is implemented using a light-activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.
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