发明申请
US20110110952A1 NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 184P1E2 USEFUL IN TREATMENT AND DETECTION OF CANCER
失效
核酸和相关蛋白质184P1E2有用的治疗和检测癌症
- 专利标题： NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 184P1E2 USEFUL IN TREATMENT AND DETECTION OF CANCER
- 专利标题（中）： 核酸和相关蛋白质184P1E2有用的治疗和检测癌症
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申请号： US12985245申请日： 2011-01-05
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公开(公告)号： US20110110952A1公开(公告)日： 2011-05-12
- 发明人: Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
- 申请人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
- 申请人地址： US CA Santa Monica
- 专利权人： AGENSYS, INC.
- 当前专利权人： AGENSYS, INC.
- 当前专利权人地址： US CA Santa Monica
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/30 ; C12N5/00 ; C12N15/63 ; C12N15/12 ; A61P35/00
摘要：
A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 184P1E2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 184P1E2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 184P1E2 can be used in active or passive immunization.
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