- 专利标题: HUMANIZED ANTI-FACTOR D ANTIBODIES AND USES THEREOF
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申请号: US13007142申请日: 2011-01-14
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公开(公告)号: US20110123528A1公开(公告)日: 2011-05-26
- 发明人: Ling-Ling An , Sek Chung Fung , Robert F. Kelley , Henry B. Lowman , Sanjaya Singh , Herren Wu
- 申请人: Ling-Ling An , Sek Chung Fung , Robert F. Kelley , Henry B. Lowman , Sanjaya Singh , Herren Wu
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/40 ; A61P27/02 ; A61P31/00 ; A61P29/00 ; A61P37/06
摘要:
The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
公开/授权文献
- US08187604B2 Methods of treating with anti-factor D antibodies 公开/授权日:2012-05-29
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