发明申请
- 专利标题: HEMOSTATIC MICROSPHERES
- 专利标题(中): 化学微球
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申请号: US12935114申请日: 2009-03-26
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公开(公告)号: US20110125089A1公开(公告)日: 2011-05-26
- 发明人: Richard I. Senderoff , Jeffrey D. Meyer , Emily N. Rollins , Steven D. Hughes , Richard M. Garcoa , Paul D. Bishop , Gerald W. Lasser
- 申请人: Richard I. Senderoff , Jeffrey D. Meyer , Emily N. Rollins , Steven D. Hughes , Richard M. Garcoa , Paul D. Bishop , Gerald W. Lasser
- 申请人地址: US WA Seattle
- 专利权人: ZYMOGENETICS, INC.
- 当前专利权人: ZYMOGENETICS, INC.
- 当前专利权人地址: US WA Seattle
- 国际申请: PCT/US2009/038320 WO 20090326
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; C07K14/00 ; A61K47/42 ; A61K38/48 ; A61K35/16 ; A61P7/00 ; B32B5/16 ; A61M5/31
摘要:
Provided herein are hemostatic compositions. In one embodiment, the hemostatic composition includes cross-linked polymer microspheres, such as cross-linked gelatin microspheres with pores. In another embodiment, the hemostatic composition comprises an additive such as a wetting agent, a suspending agent, or both. The hemostatic compositions may also include a hemostatic agent such as thrombin, and may include a high concentration of thrombin. The hemostatic compositions may also include plasma. Also provided herein are devices for dispersing said hemostatic compositions in a diluent, and delivering said dispersed hemostatic composition. The hemostatic compositions may also fabricated with a selected geometry as administration suggests.
公开/授权文献
- US09629798B2 Hemostatic microspheres 公开/授权日:2017-04-25