发明申请
- 专利标题： ANTI-FERROPORTIN 1 MONOCLONAL ANTIBODIES AND USES THEREOF
- 专利标题（中）： 抗皮质素1单克隆抗体及其用途
-
申请号： US12628263申请日： 2009-12-01
-
公开(公告)号： US20110129480A1公开(公告)日： 2011-06-02
- 发明人: Donmienne Doen Mun Leung , Peng Luan , Joseph Vincent Manetta , Ying Tang , Derrick Ryan Witcher
- 申请人： Donmienne Doen Mun Leung , Peng Luan , Joseph Vincent Manetta , Ying Tang , Derrick Ryan Witcher
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C07H21/00 ; C12N15/63 ; C12N5/07 ; C12P21/08 ; A61P7/00 ; A61P35/00
摘要：
Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.
公开/授权文献
- US08183346B2 Anti-ferroportin 1 monoclonal antibodies and uses thereof 公开/授权日：2012-05-22
信息查询
