发明申请
US20110144001A1 HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS
审中-公开
来自ACTINOMADURA NAMIBIENSIS的高度桥联蛋白
- 专利标题: HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS
- 专利标题(中): 来自ACTINOMADURA NAMIBIENSIS的高度桥联蛋白
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申请号: US12895106申请日: 2010-09-30
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公开(公告)号: US20110144001A1公开(公告)日: 2011-06-16
- 发明人: Mark BROENSTRUP , Hans GUEHRING , Holger HOFFMANN , Joachim WINK , Roderich SUESSMUTH , Timo SCHMIEDERER
- 申请人: Mark BROENSTRUP , Hans GUEHRING , Holger HOFFMANN , Joachim WINK , Roderich SUESSMUTH , Timo SCHMIEDERER
- 申请人地址: FR PARIS
- 专利权人: SANOFI-AVENTIS
- 当前专利权人: SANOFI-AVENTIS
- 当前专利权人地址: FR PARIS
- 优先权: EP08290324.6 20080402
- 主分类号: A61K38/10
- IPC分类号: A61K38/10 ; C07K7/00 ; A61P31/12 ; A61P31/04 ; C12N15/31 ; A61P29/00
摘要:
The invention refers to so-called Labyrinthopeptin derivatives of the formula (I) wherein {A}, {B}, {C}, R1-R6, m and n are as defined herein, obtainable from microorganism strain Actinomadura namibiensis (DSM 6313), its use for the treatment of bacterial infections, viral infections and/or pain, a pharmaceutical composition comprising it, prepro-Labyrinthopeptin, pro-Labyrinthopeptin, and DNA coding for prepro-Labyrinthopeptin and pro-Labyrinthopeptin.