发明申请
US20110160259A1 Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
失效
抑制BCL蛋白与结合伙伴相互作用的化合物和方法
- 专利标题： Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
- 专利标题（中）： 抑制BCL蛋白与结合伙伴相互作用的化合物和方法
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申请号： US12956969申请日： 2010-11-30
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公开(公告)号： US20110160259A1公开(公告)日： 2011-06-30
- 发明人: Alfredo C. Castro , Edward B. Holson , Brian T. Hopkins , Nii O. Koney , Daniel A. Snyder , Thomas T. Tibbitts
- 申请人： Alfredo C. Castro , Edward B. Holson , Brian T. Hopkins , Nii O. Koney , Daniel A. Snyder , Thomas T. Tibbitts
- 申请人地址： US MA Cambridge
- 专利权人： Infinity Discovery, Inc.
- 当前专利权人： Infinity Discovery, Inc.
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/42
- IPC分类号： A61K31/42 ; A61K31/422 ; A61P35/00 ; A61P35/02 ; A61P35/04
摘要：
One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.