发明申请
- 专利标题： RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID
- 专利标题（中）： 重组细胞生产2-羟基丁酸
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申请号： US13001204申请日： 2009-04-28
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公开(公告)号： US20110171702A1公开(公告)日： 2011-07-14
- 发明人: Liv Reinecke , Steffen Schaffer , Achim Marx , Markus Poetter , Thomas Haas
- 申请人： Liv Reinecke , Steffen Schaffer , Achim Marx , Markus Poetter , Thomas Haas
- 申请人地址： DE Darmstadt
- 专利权人： EVONIK ROEHM GMBH
- 当前专利权人： EVONIK ROEHM GMBH
- 当前专利权人地址： DE Darmstadt
- 优先权： DE102008002715.4 20080627
- 国际申请： PCT/EP2009/055089 WO 20090428
- 主分类号： C12P7/40
- IPC分类号： C12P7/40 ; C12N5/10 ; C12N1/00 ; C12P7/42 ; C12P7/62
摘要：
The invention relates to a cell which has been genetically modified so as to be capable of producing more 2-hydroxyisobutyric acid or more polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units than its wild type, characterized in that 2-hydroxyisobutyric acid or polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units are produced via acetoacetyl-coenzyme A as intermediate and 3-hydroxybutyryl-coenzyme A as precursor.
公开/授权文献
- US10174349B2 Recombinant cell producing 2-hydroxyisobutyric acid 公开/授权日：2019-01-08
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