发明申请
US20110177996A1 REGULATORY PROTEINS IN LUNG REPAIR AND TREATMENT OF LUNG DISEASE
审中-公开
肺部修复和治疗肺病的监管蛋白
- 专利标题： REGULATORY PROTEINS IN LUNG REPAIR AND TREATMENT OF LUNG DISEASE
- 专利标题（中）： 肺部修复和治疗肺病的监管蛋白
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申请号： US11915229申请日： 2006-05-23
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公开(公告)号： US20110177996A1公开(公告)日： 2011-07-21
- 发明人: Jeffrey A. Whitsett , James Wells
- 申请人： Jeffrey A. Whitsett , James Wells
- 申请人地址： US OH Cincinnati
- 专利权人： CHILDREN'S HOSPITAL MEDICAL CENTER
- 当前专利权人： CHILDREN'S HOSPITAL MEDICAL CENTER
- 当前专利权人地址： US OH Cincinnati
- 国际申请： PCT/US2006/020512 WO 20060523
- 主分类号： A61K38/02
- IPC分类号： A61K38/02 ; C07K2/00 ; C07H21/00 ; A61K31/7088 ; C12N5/071 ; C12Q1/02 ; A61P11/00
摘要：
The DNA-binding protein Sox17 has been found to play an important role in repair of pulmonary tissue after damage, disease, or injury. Nucleic acids encoding proteins involved in pulmonary repair, such as Sox17 and Spdef, can be used as a therapeutic composition for treating pulmonary disease. Methods of treatment of pulmonary injuries or pulmonary diseases are also disclosed, as are methods of identifying compounds effective in treating pulmonary injuries and diseases.
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