发明申请
US20110178007A1 SPIRO-IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS
有权
SPIRO-IMIDAZOLONE衍生物作为GLUCAGON受体拮抗剂
- 专利标题： SPIRO-IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS
- 专利标题（中）： SPIRO-IMIDAZOLONE衍生物作为GLUCAGON受体拮抗剂
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申请号： US13121725申请日： 2009-09-30
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公开(公告)号： US20110178007A1公开(公告)日： 2011-07-21
- 发明人: Andrew Stamford , Michael W Miller , Duane Eugene Demong , William J Greenlee , Joseph A Kozlowski , Brian J Lavey , Michael K.C. Wong , Wensheng Yu , Xing Dai , De-Yi Yang , Guowei Zhou
- 申请人： Andrew Stamford , Michael W Miller , Duane Eugene Demong , William J Greenlee , Joseph A Kozlowski , Brian J Lavey , Michael K.C. Wong , Wensheng Yu , Xing Dai , De-Yi Yang , Guowei Zhou
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 国际申请： PCT/US09/58963 WO 20090930
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; C07D235/02 ; C07D403/12 ; C07D491/107 ; A61K31/4188 ; C07D401/14 ; A61K31/4439 ; C07F7/10 ; A61K31/695 ; C07D405/14 ; C07D405/04 ; A61K31/4709 ; A61K38/28 ; A61K38/16 ; A61K38/22 ; A61K31/7034 ; A61K31/70 ; A61K31/7048 ; A61P3/10
摘要：
The present invention relates to compounds of the general formula: (I) wherein ring A, ring B, R1, R3, Z, L1, and L2 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and to methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.
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