发明申请
- 专利标题： Muscle-specific expression vectors
- 专利标题（中）： 肌肉特异性表达载体
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申请号： US11716899申请日： 2007-03-12
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公开(公告)号： US20110212529A1公开(公告)日： 2011-09-01
- 发明人: David Souza , Donna Armentano
- 申请人： David Souza , Donna Armentano
- 主分类号： C12N15/85
- IPC分类号： C12N15/85 ; C07H21/04 ; C12N1/00 ; C12N5/10
摘要：
The invention is directed to novel combinations of muscle-specific enhancers and promoter elements useful for achieving persistent expression in the muscle or myocyctes. The muscle-specific promoter elements are derived from a muscle creatine kinase promoter, a troponin I promoter, a skeletal alpha-actin promoter, or a desmin promoter. The muscle-specific enhancer elements are derived from either troponin I internal regulatory elements, muscle creatine kinase enhancers, or desmin enhancers.
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