发明申请
- 专利标题: PHARMACEUTICAL COMPOSITION SIMULTANEOUSLY HAVING RAPID-ACTING PROPERTY AND LONG-ACTING PROPERTY
- 专利标题(中): 药物组合物同时具有快速作用的物质和长效能
-
申请号: US13108050申请日: 2011-05-16
-
公开(公告)号: US20110217374A1公开(公告)日: 2011-09-08
- 发明人: Dong-Joon OH , Byoung-Ki Kim , Byung-Kwan Moon , Ji-Seok Yoo , Dae-Hee Shin , Byung-Hwan Ryoo
- 申请人: Dong-Joon OH , Byoung-Ki Kim , Byung-Kwan Moon , Ji-Seok Yoo , Dae-Hee Shin , Byung-Hwan Ryoo
- 申请人地址: KR Seoul
- 专利权人: YUNGJIN PHARM. CO., LTD.
- 当前专利权人: YUNGJIN PHARM. CO., LTD.
- 当前专利权人地址: KR Seoul
- 优先权: KR10-2009-0096315 20091009; KR10-2009-0104248 20091030
- 主分类号: A61K9/22
- IPC分类号: A61K9/22 ; A61K31/167 ; A61K31/522 ; A61K31/4545 ; A61K31/4453 ; A61K31/135 ; A61K31/455 ; A61K31/47 ; A61K31/505 ; A61K31/40 ; A61K31/4704 ; A61K31/64 ; A61K31/155 ; A61K31/4439 ; A61K31/4985 ; A61K31/685 ; A61K9/00
摘要:
Disclosed is a pharmaceutical composition simultaneously having a rapid acting property and a long-acting property, comprising a sustained-release part coated with a water-insoluble polymer on the surface, comprising a first active pharmaceutical ingredient, at least one release control base selected from the group consisting of water-insoluble polymer, and water-soluble viscous polymer, and a pharmaceutically acceptable carrier; and, an immediate release part comprising a second active pharmaceutical ingredient and a pharmaceutically acceptable carrier. The pharmaceutical composition exhibits independent release properties of the immediate release part and the sustained-release part by coating the surface of the sustained-release part comprising an active pharmaceutical ingredient, a release control base and a pharmaceutically acceptable carrier with a water-insoluble polymer to separate it from the immediate release part, and it may be prepared by a relatively simple process without specification limitation to the contents and the kinds of usable pharmaceutically active ingredients.