发明申请
- 专利标题： RNA ANTAGONISTS TARGETING HSP70-2
- 专利标题（中）： RNA拮抗剂靶向HSP70-2
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申请号： US12999597申请日： 2009-06-18
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公开(公告)号： US20110224281A1公开(公告)日： 2011-09-15
- 发明人: Anja Molhart Hog , Jens Bo Hansen
- 申请人： Anja Molhart Hog , Jens Bo Hansen
- 优先权： EP08104472.9 20080619
- 国际申请： PCT/EP09/57569 WO 20090618
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; C07H21/00 ; A61P35/00 ; C12N5/071
摘要：
The present invention relates to LNA oligomer compounds (oligomers), which target Hsp70 and mRNA in a cell, leading to reduced expression of Hsp70. Reduction of Hsp70 expression is beneficial for the treatment of certain medical disorders, such as hyperproliferative diseases, such as cancer.
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