发明申请
US20110229471A1 METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNF ALPHA THERAPY IN INFLAMMATORY BOWEL DISEASE
审中-公开
在炎症性皮肤疾病中测定抗TNF ALPHA治疗的反应方法
- 专利标题： METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNF ALPHA THERAPY IN INFLAMMATORY BOWEL DISEASE
- 专利标题（中）： 在炎症性皮肤疾病中测定抗TNF ALPHA治疗的反应方法
-
申请号： US13130998申请日： 2009-11-25
-
公开(公告)号： US20110229471A1公开(公告)日： 2011-09-22
- 发明人: Jerome I. Rotter , Marla Dubinsky , Stephan R. Targan , Kent D. Taylor
- 申请人： Jerome I. Rotter , Marla Dubinsky , Stephan R. Targan , Kent D. Taylor
- 申请人地址： US CA Los Angeles
- 专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人地址： US CA Los Angeles
- 国际申请： PCT/US09/65928 WO 20091125
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12Q1/68 ; A61P29/00
摘要：
The present invention relates to methods of prognosing responsiveness to anti-TNFα therapy by determining the presence or absence of risk factors in the individual. In one embodiment, the risk factors are genetic markers, serological markers and/or clinical phenotypes associated with non-responsiveness to treatment with anti-TNFα therapy in an individual diagnosed with IBD.
信息查询
