发明申请
- 专利标题: METHOD FOR LOWERING THE DEPENDENCY TOWARDS SEQUENCE VARIATION OF A NUCLEIC ACID TARGET IN A DIAGNOSTIC HYBRIDIZATION ASSAY
- 专利标题(中): 降低依赖性在诊断杂交测定中核酸核酸靶序列变异的方法
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申请号: US13058979申请日: 2009-09-21
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公开(公告)号: US20110236892A1公开(公告)日: 2011-09-29
- 发明人: Birgit Deiman , Dianne Van Strijp
- 申请人: Birgit Deiman , Dianne Van Strijp
- 申请人地址: FR MARCY L'ETOILE
- 专利权人: BIOMERIEUX
- 当前专利权人: BIOMERIEUX
- 当前专利权人地址: FR MARCY L'ETOILE
- 优先权: EP08016733.1 20080924
- 国际申请: PCT/EP2009/062206 WO 20090921
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H21/00 ; C12P19/34
摘要:
A primer or/and probe for a target sequence containing at least one variation, defined as either one non-conserved nucleotide, called genotype variation, or one nucleotide variation within one and the same genotype, wherein the primer or/and probe has a nucleic acid sequence that is complementary to said target sequence except for the at least complementary base of the variation(s), which is not present in the primer or/and probe.
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