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公开(公告)号：US08822152B2
公开(公告)日：2014-09-02
申请号：US12513955
申请日：2007-11-07
CPC分类号： C12Q1/6865 , C12Q2537/143 , C12Q2525/186
摘要： The present invention is in the field of nucleic acid amplification, and in particular in transcription-based amplification, providing improvements thereof. Specifically, the present invention provides primers, and methods for using them, that improve transcription-based amplification reactions, in particular multiplex reactions.
摘要翻译： 本发明在核酸扩增领域，特别是在基于转录的扩增中，提供了其改进。 具体地说，本发明提供了改进基于转录的扩增反应，特别是多重反应的引物及其使用方法。
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2.发明申请公开(公告)号：US20100143882A1
公开(公告)日：2010-06-10
申请号：US12513955
申请日：2007-11-07
CPC分类号： C12Q1/6865 , C12Q2537/143 , C12Q2525/186
摘要： The present invention is in the field of nucleic acid amplification, and in particular in transcription-based amplification, providing improvements thereof. Specifically, the present invention provides primers, and methods for using them, that improve transcription-based amplification reactions, in particular multiplex reactions.
摘要翻译： 本发明在核酸扩增领域，特别是在基于转录的扩增中，提供了其改进。 具体地说，本发明提供了改进基于转录的扩增反应，特别是多重反应的引物及其使用方法。
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公开(公告)号：US20090203013A1
公开(公告)日：2009-08-13
申请号：US12339471
申请日：2008-12-19
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/6844 , C12Q2600/106 , C12Q2600/156 , C12Q2600/16
摘要： The present invention provides improved tests for the detection of methicillin-resistant Staphylococcus aureus. The tests are particularly useful for eliminating false positive results due to the presence of a mixed bacterial population in patient samples.
摘要翻译： 本发明提供了用于检测耐甲氧西林金黄色葡萄球菌的改进试验。 由于在患者样品中存在混合细菌群，这些检测对于消除假阳性结果特别有用。
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公开(公告)号：US08367337B2
公开(公告)日：2013-02-05
申请号：US12339471
申请日：2008-12-19
CPC分类号： C12Q1/689 , C12Q1/6844 , C12Q2600/106 , C12Q2600/156 , C12Q2600/16
摘要： The present invention provides improved tests for the detection of methicillin-resistant Staphylococcus aureus. The tests are particularly useful for eliminating false positive results due to the presence of a mixed bacterial population in patient samples.
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5.发明申请METHOD FOR LOWERING THE DEPENDENCY TOWARDS SEQUENCE VARIATION OF A NUCLEIC ACID TARGET IN A DIAGNOSTIC HYBRIDIZATION ASSAY 审中-公开降低依赖性在诊断杂交测定中核酸核酸靶序列变异的方法公开(公告)号：US20110236892A1
公开(公告)日：2011-09-29
申请号：US13058979
申请日：2009-09-21
申请人： Birgit Deiman , Dianne Van Strijp
发明人： Birgit Deiman , Dianne Van Strijp
CPC分类号： C12Q1/6876 , C12Q2600/156
摘要： A primer or/and probe for a target sequence containing at least one variation, defined as either one non-conserved nucleotide, called genotype variation, or one nucleotide variation within one and the same genotype, wherein the primer or/and probe has a nucleic acid sequence that is complementary to said target sequence except for the at least complementary base of the variation(s), which is not present in the primer or/and probe.
摘要翻译： 用于靶序列的引物或/和探针，其含有至少一个定义为一个非保守核苷酸，称为基因型变异或一个和相同基因型内的一个核苷酸变异的变异体，其中该引物或/和探针具有核酸 除了引物或/和探针中不存在的变体的至少互补碱基之外，与所述靶序列互补的酸序列。
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