发明申请
US20110237589A1 GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS
有权
胍基化合物及其作为5-HT5受体的结合合作伙伴使用
- 专利标题： GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS
- 专利标题（中）： 胍基化合物及其作为5-HT5受体的结合合作伙伴使用
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申请号： US13021336申请日： 2011-02-04
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公开(公告)号： US20110237589A1公开(公告)日： 2011-09-29
- 发明人: Astrid Netz , Wilhelm Amberg , Udo Lange , Michael Ochse , Charles W. Hutchins , Francisco-Xavier Garcia-Ladona , Wolfgang Wernet , Andreas Kling , Andrea Hager-Wernet
- 申请人： Astrid Netz , Wilhelm Amberg , Udo Lange , Michael Ochse , Charles W. Hutchins , Francisco-Xavier Garcia-Ladona , Wolfgang Wernet , Andreas Kling , Andrea Hager-Wernet
- 优先权： DE102004008141.7 20040219
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D277/38 ; A61K31/426 ; C07D417/02 ; A61K31/4439 ; C07D235/30 ; A61K31/416 ; A61K31/428 ; C07D285/08 ; A61K31/433 ; C07D417/04 ; A61K31/506 ; C07D413/02 ; A61K31/454 ; C07D263/48 ; A61K31/421 ; A61P25/00 ; A61P9/10 ; A61P25/28 ; A61P25/22 ; A61P25/24 ; A61P35/00
摘要：
The present invention relates to guanidine compounds of the general formula I corresponding enantiomeric, diastereomeric and/or tautomeric forms thereof as well as pharmaceutically acceptable salts thereof. The present compound further relates to the use of guanidine compounds as binding partners for 5-HT5 receptors for the treatment of diseases which are modulated by a 5-HT5 receptor activity, in particular for the treatment of neurodegenerative and neuropsychiatric disorders as well as the associated signs, symptoms and dysfunctions.
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