发明申请
- 专利标题： NEUTRALIZING ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
- 专利标题（中）： 中和抗GDF-8抗体及其用途
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申请号： US12632383申请日： 2009-12-07
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公开(公告)号： US20110243953A1公开(公告)日： 2011-10-06
- 发明人: Geertruida M. Veldman , Monique V. Davies , Kening Song , Neil M. Wolfman , Kristie Grove Bridges , Anne Field , Caroline Russell , Viia Valge-Archer
- 申请人： Geertruida M. Veldman , Monique V. Davies , Kening Song , Neil M. Wolfman , Kristie Grove Bridges , Anne Field , Caroline Russell , Viia Valge-Archer
- 申请人地址： US NJ Madison GB Cambridge
- 专利权人： Wyeth,Medlmmune Limited
- 当前专利权人： Wyeth,Medlmmune Limited
- 当前专利权人地址： US NJ Madison GB Cambridge
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/22 ; C07H21/04 ; A61P21/00 ; A61P19/08 ; A61P11/00 ; A61P3/10 ; C12N15/63 ; C12N5/10 ; C12N1/00 ; C12P21/02 ; A61P3/04 ; A61P3/00
摘要：
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.
公开/授权文献
- US08420082B2 Neutralizing antibodies against GDF-8 and uses therefor 公开/授权日：2013-04-16
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