Invention Application
US20110250192A1 USE OF MICRORNA SIGNATURES FOR ASSESSING RISK LEVELS OF NEUROBLASTOMA PATIENTS
审中-公开
使用MICRORNA标志评估神经损伤患者的风险水平
- Patent Title: USE OF MICRORNA SIGNATURES FOR ASSESSING RISK LEVELS OF NEUROBLASTOMA PATIENTS
- Patent Title (中): 使用MICRORNA标志评估神经损伤患者的风险水平
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Application No.: US13056043Application Date: 2009-08-03
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Publication No.: US20110250192A1Publication Date: 2011-10-13
- Inventor: Alice L. Yu , You-Chin Lin , Ruey-Jen Lin
- Applicant: Alice L. Yu , You-Chin Lin , Ruey-Jen Lin
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- International Application: PCT/US2009/052550 WO 20090803
- Main IPC: A61K38/46
- IPC: A61K38/46 ; A61K48/00 ; A61P35/00 ; C12Q1/68
Abstract:
Methods for assessing the risk level or survival/death probability of a neuroblastoma patient based on a number of microRNA signatures, optionally in combination with Dicer, Drosha, and age at diagnosis. Also disclosed herein is use of Dicer, Drosha, or both in suppressing neuroblastoma cell growth
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