公开(公告)号：US20110250192A1

公开(公告)日：2011-10-13

申请号：US13056043

申请日：2009-08-03

Applicant: Alice L. Yu ,  You-Chin Lin ,  Ruey-Jen Lin

Inventor： Alice L. Yu ,  You-Chin Lin ,  Ruey-Jen Lin

IPC: A61K38/46 ,  A61K48/00 ,  A61P35/00 ,  C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/178

Abstract: Methods for assessing the risk level or survival/death probability of a neuroblastoma patient based on a number of microRNA signatures, optionally in combination with Dicer, Drosha, and age at diagnosis. Also disclosed herein is use of Dicer, Drosha, or both in suppressing neuroblastoma cell growth

Abstract translation: 基于许多微小RNA标记来评估神经母细胞瘤患者的风险水平或存活/死亡概率的方法，任选地与Dicer，Drosha和诊断年龄组合。 本文还公开了使用Dicer，Drosha或两者来抑制神经母细胞瘤细胞生长