发明申请
- 专利标题： Contrast agents endowed with high relaxivity
- 专利标题（中）： 对比剂具有高的放松性
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申请号： US11630600申请日： 2005-06-28
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公开(公告)号： US20110256067A1公开(公告)日： 2011-10-20
- 发明人: Silvio Aime , Matteo Galli , Luciano Lattuada , Pierfrancesco Morosini , Fulvio Uggeri , Kondareddiar Ramalingam
- 申请人： Silvio Aime , Matteo Galli , Luciano Lattuada , Pierfrancesco Morosini , Fulvio Uggeri , Kondareddiar Ramalingam
- 申请人地址： IT Milano
- 专利权人： Bracco Imaging SpA
- 当前专利权人： Bracco Imaging SpA
- 当前专利权人地址： IT Milano
- 国际申请： PCT/EP05/06956 WO 20050628
- 主分类号： A61K49/10
- IPC分类号： A61K49/10 ; C07F5/00 ; C07D243/10 ; C07H15/26 ; C07D243/08
摘要：
The present invention relates to a novel class of paramagnetic ion-based contrast agents of formula (I), wherein a chelating backbone moiety is highly functionalized by the presence of one or more polyhydroxylated chain, that show a pharmacokinetic profile analogous to that of the commonly used T1-general extravascular agents (NSA) but are further characterized by a higher relaxivity.
公开/授权文献
- US08540966B2 Contrast agents endowed with high relaxivity 公开/授权日：2013-09-24
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