发明申请
US20110268805A1 ADJUVANT INCORPORATION IN IMMUNONANOTHERAPEUTICS
有权
ADJUVANT INCORPORATION IN IMMUNANANOTHERAPEUTICS
- 专利标题： ADJUVANT INCORPORATION IN IMMUNONANOTHERAPEUTICS
- 专利标题（中）： ADJUVANT INCORPORATION IN IMMUNANANOTHERAPEUTICS
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申请号： US13123888申请日： 2009-10-09
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公开(公告)号： US20110268805A1公开(公告)日： 2011-11-03
- 发明人: Frank Alexis , Matteo Iannacone , Jinjin Shi , Pamela Basto , Elliott Ashley Moseman , Ulrich von Andrian , Robert S. Langer , Omid C. Farokhzad , Elena Tonti
- 申请人： Frank Alexis , Matteo Iannacone , Jinjin Shi , Pamela Basto , Elliott Ashley Moseman , Ulrich von Andrian , Robert S. Langer , Omid C. Farokhzad , Elena Tonti
- 优先权： USPCT/US2008/011932 20081012; US12/428395 20090422
- 国际申请： PCT/US09/60242 WO 20091009
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K39/39 ; A61K38/21 ; A61P37/04 ; A61K38/20 ; A61K39/02 ; A61K39/12 ; A61K39/00 ; A61K39/002
摘要：
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is an adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.
公开/授权文献
- US08637028B2 Adjuvant incorporation in immunonanotherapeutics 公开/授权日：2014-01-28
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