发明申请
US20110275636A1 DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
有权
作为金属螯合剂的DESAZADESFERROTHIOCIN和DESAZADESFERROTHIOCIN聚醚类似物
- 专利标题： DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
- 专利标题（中）： 作为金属螯合剂的DESAZADESFERROTHIOCIN和DESAZADESFERROTHIOCIN聚醚类似物
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申请号： US13100705申请日： 2011-05-04
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公开(公告)号： US20110275636A1公开(公告)日： 2011-11-10
- 发明人: James Malecha
- 申请人： James Malecha
- 申请人地址： US CA San Carlos
- 专利权人： FerroKin BioSciences, Inc.
- 当前专利权人： FerroKin BioSciences, Inc.
- 当前专利权人地址： US CA San Carlos
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/421 ; C07D233/28 ; A61K31/4172 ; C07D231/14 ; A61K31/415 ; C07D277/12 ; A61K31/426 ; C07D413/10 ; C07D417/10 ; A61K31/496 ; A61P7/06 ; A61P3/10 ; A61P1/16 ; A61P31/14 ; C07D263/16
摘要：
Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
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