发明申请
US20110295299A1 GASTRIC VOLUME FILLING CONSTRUCT 审中-公开
气体填充结构

GASTRIC VOLUME FILLING CONSTRUCT
摘要:
The technology described herein provides methods for addressing obesity by introducing a device into the stomach. Embodiments of a device for treating obesity may comprise a shaped membrane construct that contains a swellable material. The construct may be contained within a capsule which is ingested by a patient. When the capsule dissolves in the stomach, the gastric secretions may diffuse through the membrane and spontaneously swell the internal material, which swells and stiffens the construct sufficiently to create a sensation of satiety by both filling gastric volume and by distending the walls of the stomach. The volume of the construct may be sufficient to prevent passage through the pyloric sphincter. After a set period of time or after the administration of a degradation formulation, the device may structurally degrade to allow passage through the pyloric sphincter and eventual passage from the body.
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