发明申请
- 专利标题: GENE CARRIER
- 专利标题(中): 基因载体
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申请号: US13214580申请日: 2011-08-22
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公开(公告)号: US20110301230A1公开(公告)日: 2011-12-08
- 发明人: Kazuo SAKURAI , Seiji Shinkai , Taro Kimura , Kengo Tabata , Kazuya Koumoto , Oliver Gronwald
- 申请人: Kazuo SAKURAI , Seiji Shinkai , Taro Kimura , Kengo Tabata , Kazuya Koumoto , Oliver Gronwald
- 申请人地址: JP Tokyo JP Kawaguchi-shi
- 专利权人: TAITO CO., LTD,JAPAN SCIENCE AND TECHNOLOGY CORPORATION
- 当前专利权人: TAITO CO., LTD,JAPAN SCIENCE AND TECHNOLOGY CORPORATION
- 当前专利权人地址: JP Tokyo JP Kawaguchi-shi
- 优先权: JP11-319470 19991110; JP12-142897 20000516
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C07H21/04 ; C12N5/00 ; C07H21/02
摘要:
Disclosed is a gene carrier composed of a hydrogen-bonding polymer having a polymer chain with hydrogen-bonding sites formed on the polymer chain, in which the polymer chain has a conformation similar to the conformation of a nucleic acid, and particularly, the polymer chain has helix parameters similar to the helix parameters of a nucleic acid of a helix structure. In a preferred embodiment, the hydrogen-bonding polymer is composed of β-1,3-glucan such as schizophyllan. The carrier can be expected to be applied as a vector and a separator for nucleic acids because it is capable of interacting with a nucleic acid to form a complex with the nucleic acid and thus carrying the nucleic acid.