发明申请
US20110319499A1 Methods for the Detection of Advanced Glycation Endproducts and Markers for Disease
审中-公开
检测高级糖基化终产物和疾病标志物的方法
- 专利标题： Methods for the Detection of Advanced Glycation Endproducts and Markers for Disease
- 专利标题（中）： 检测高级糖基化终产物和疾病标志物的方法
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申请号： US13002106申请日： 2009-06-30
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公开(公告)号： US20110319499A1公开(公告)日： 2011-12-29
- 发明人: Richard David Semba , Luigi Ferruci , Edward G. Lakatta
- 申请人： Richard David Semba , Luigi Ferruci , Edward G. Lakatta
- 申请人地址： US MD Baltimore
- 专利权人： THE JOHNS HOPKINS UNIVERSITY
- 当前专利权人： THE JOHNS HOPKINS UNIVERSITY
- 当前专利权人地址： US MD Baltimore
- 国际申请： PCT/US09/03923 WO 20090630
- 主分类号： A61K47/40
- IPC分类号： A61K47/40 ; G01N33/566 ; A61K47/16 ; A61K47/42 ; A61P3/10 ; A61K47/14 ; A61K47/02 ; A61K47/04 ; A61P13/12 ; A61P9/10 ; G01N33/53 ; A61K47/38
摘要：
The present invention provides compositions and methods for detecting carboxymethyl-lysine (CML) and circulating receptor for advanced glycation end (RAGE) products, and methods for correlating CML and RAGE levels with age-related disease, hi particular, serum CML and/or circulating receptor for advanced glycation end (RAGE) products can be used as a clinical biomarker in diagnostics to identify people who are at a higher risk of developing adverse ageing-related outcomes.
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