发明申请
US20120009172A1 INTRAVENOUS AND ORAL DOSING OF A DIRECT-ACTING AND REVERSIBLE P2Y12 INHIBITOR
审中-公开
直接作用和可逆的P2Y12抑制剂的口服和口服剂量
- 专利标题: INTRAVENOUS AND ORAL DOSING OF A DIRECT-ACTING AND REVERSIBLE P2Y12 INHIBITOR
- 专利标题(中): 直接作用和可逆的P2Y12抑制剂的口服和口服剂量
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申请号: US13235305申请日: 2011-09-16
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公开(公告)号: US20120009172A1公开(公告)日: 2012-01-12
- 发明人: Daniel D. Gretler , Pamela B. Conley , Patrick Andre , Athiwat Hutchaleelaha , David R. Phillips , Anjali Pandey , Robert M. Scarborough , Carroll Anna Crew Scarborough , Wolin Huang
- 申请人: Daniel D. Gretler , Pamela B. Conley , Patrick Andre , Athiwat Hutchaleelaha , David R. Phillips , Anjali Pandey , Robert M. Scarborough , Carroll Anna Crew Scarborough , Wolin Huang
- 申请人地址: US CA So. San Francisco
- 专利权人: Portola Pharmaceuticals, Inc.
- 当前专利权人: Portola Pharmaceuticals, Inc.
- 当前专利权人地址: US CA So. San Francisco
- 主分类号: A61K38/45
- IPC分类号: A61K38/45 ; A61K38/48 ; A61P9/00 ; A61K31/517 ; C07D409/12 ; A61P7/00 ; A61K38/46 ; A61K31/60
摘要:
The invention provides methods and compositions for rapid and reversible inhibition of platelet aggregation in human subjects in need thereof by administering compounds of the formula: alone or in combination with a second agent which can be aspirin or a thrombolytic agent.
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