发明申请
- 专利标题： HIV DNA Vaccine Methods of Use
- 专利标题（中）： HIV DNA疫苗使用方法
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申请号： US13185158申请日： 2011-07-18
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公开(公告)号： US20120021000A1公开(公告)日： 2012-01-26
- 发明人: Opendra Narayan , Zhenqian Liu
- 申请人： Opendra Narayan , Zhenqian Liu
- 申请人地址： US KS Kansas City
- 专利权人： UNIVERSITY OF KANSAS MEDICAL CENTER
- 当前专利权人： UNIVERSITY OF KANSAS MEDICAL CENTER
- 当前专利权人地址： US KS Kansas City
- 主分类号： A61K39/21
- IPC分类号： A61K39/21 ; A61K31/711 ; A61P31/18
摘要：
The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3′ LTR.
公开/授权文献
- US08785411B2 HIV DNA vaccine methods of use 公开/授权日：2014-07-22
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