发明申请
US20120028248A1 ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING
有权
用于DNA测序的工程化荧光染料标记核苷类似物
- 专利标题: ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING
- 专利标题(中): 用于DNA测序的工程化荧光染料标记核苷类似物
-
申请号: US13115284申请日: 2011-05-25
-
公开(公告)号: US20120028248A1公开(公告)日: 2012-02-02
- 发明人: Gene Shen , Paul Peluso , Arkadusz Bibillo
- 申请人: Gene Shen , Paul Peluso , Arkadusz Bibillo
- 申请人地址: US CA Menlo Park
- 专利权人: Pacific Biosciences of California, Inc.
- 当前专利权人: Pacific Biosciences of California, Inc.
- 当前专利权人地址: US CA Menlo Park
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H19/207 ; C07H19/10
摘要:
Engineered nucleotide compositions, having polymerase interacting components that improve the interactivity of the polymerase and the nucleotide, particularly for nucleic acid sequencing applications. Compositions include the interactive polymerases along with the nucleotide analogs. Kits, methods and systems are provided for analysis of nucleoc acid synthesis reactions.