发明申请
- 专利标题: ANTI-MST1R ANTIBODIES AND USES THEREOF
- 专利标题(中): ANTI-MST1R抗体及其用途
-
申请号: US13206736申请日: 2011-08-10
-
公开(公告)号: US20120034215A1公开(公告)日: 2012-02-09
- 发明人: Reimi Kawaida , Toshiaki Ohtsuka , Toshinori Agatsuma , Philip Rodley , Sandra Miller , Ulrike Schubert
- 申请人: Reimi Kawaida , Toshiaki Ohtsuka , Toshinori Agatsuma , Philip Rodley , Sandra Miller , Ulrike Schubert
- 申请人地址: JP Tokyo
- 专利权人: DAIICHI SANKYO COMPANY, LIMITED
- 当前专利权人: DAIICHI SANKYO COMPANY, LIMITED
- 当前专利权人地址: JP Tokyo
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12N15/13 ; A61P35/00 ; C12P21/00 ; C12N5/10 ; C12N1/21 ; C12N5/071 ; C07K16/28 ; C12N15/63
摘要:
The present disclosure provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for MST1R, which plays an integral role in various disorders or conditions, such as cancer. These antibodies, accordingly, can be used to treat these and other disorders and conditions. Antibodies of the disclosure also can be used in the diagnostics field, as well as for further investigating the role of MST1R in the progression of disorders associated with tumors. The disclosure also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use.
公开/授权文献
- US09403909B2 Anti-MST1R antibodies and uses thereof 公开/授权日:2016-08-02