Invention Application
US20120034235A1 Marker for Liver-Cancer Diagnosis and Recurrence and Survival Prediction, a Kit Comprising the Same, and Prognosis Prediction in Liver-Cancer Patients Using the Marker
审中-公开
用于肝癌诊断和复发和生存预测的标记物，包含其的试剂盒和使用标记物的肝癌患者的预后预测
- Patent Title: Marker for Liver-Cancer Diagnosis and Recurrence and Survival Prediction, a Kit Comprising the Same, and Prognosis Prediction in Liver-Cancer Patients Using the Marker
- Patent Title (中): 用于肝癌诊断和复发和生存预测的标记物，包含其的试剂盒和使用标记物的肝癌患者的预后预测
-
Application No.: US13145773Application Date: 2010-01-22
-
Publication No.: US20120034235A1Publication Date: 2012-02-09
- Inventor: Kee Ho Lee , Eun Ran Park , Pu Hyeon Cha , Sang Bum Kim , Sun Hoo Park , Dong Hyoung Lee , Seon Rang Woo , Chul Ju Han , Yong Ho Ham , Eun Ju Lee , Myoung Jin Park , Sang Gu Hwang , Hyun Jin Shin
- Applicant: Kee Ho Lee , Eun Ran Park , Pu Hyeon Cha , Sang Bum Kim , Sun Hoo Park , Dong Hyoung Lee , Seon Rang Woo , Chul Ju Han , Yong Ho Ham , Eun Ju Lee , Myoung Jin Park , Sang Gu Hwang , Hyun Jin Shin
- Applicant Address: KR Seoul
- Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
- Current Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
- Current Assignee Address: KR Seoul
- Priority: KR10-2009-0005693 20090122
- International Application: PCT/KR2010/000442 WO 20100122
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12Q1/26 ; A61P35/00 ; C40B40/10 ; C40B30/04 ; C12Q1/68 ; G01N33/573
Abstract:
A composition for detecting a marker for the diagnosis or prognosis of liver cancer is disclosed. The composition includes an agent capable of assessing the expression level of UQCRH (ubiquinol-cytochrome c reductase hinge protein). In addition, a kit having the composition, a microarray for the diagnosis of liver cancer using the marker, and a method for detecting the marker, and predicting recurrence following surgery in liver cancer patients are disclosed. The marker is able to contribute to the early diagnosis of liver cancer and prediction of recurrence following surgery and survival of liver cancer patients who have undergone hepatic resection, and also is significant for being a promising therapeutic target for liver cancer.
Information query
