A method of forming a multi-layer paint film comprising coating an aqueous first colored base paint (A) on an electro-deposition paint cured paint film to form a first colored base paint film, coating an aqueous second colored base paint (B) on the first colored base paint film without preliminary heating of the first colored base paint film to form a second colored base paint film, coating a clear paint (C) coated on the second colored base paint film after preliminary heating of the first paint film and second paint film to form a clear paint film, and heating and curing the three paint films at the same time, wherein a talc pigment is included in each of paint (A) and paint (B) in an amount of from 1 to 5 mass % with respect to the total resin solid fraction of each of paint (A) and paint (B).